HitPredict

Interactor 1: HIRA (P79987)
Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1)
Gene: HIRA

Interactor 2: ASF1 (Q3C1E9)
Histone chaperone ASF1 (Anti-silencing function protein 1 homolog)
Gene: ASF1

Species: Gallus gallus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	14652010, 16537536
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1019 Gg			1 204
+	Hs
		867906 HIRA_HUMAN (1-1019): 0: 780: 85.41		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Hs
		867897 HIRA_HUMAN (1-1019): 0: 780: 85.41		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Xl
		1148535 HIRA_XENLA (1-1019): 0: 746: 79.53		AS1AA_XENLA (1-204): 2.01e-123: 348: 92.65
+	At
		1321245 HIRA_ARATH (173-1017): 6.68e-133: 428: 16.27		ASF1A_ARATH (1-172): 1.71e-91: 267: 55.81
+	Sp
		251629 HIR1_SCHPO (128-1002): 2.58e-122: 398: 16.70		ASF1_SCHPO (1-169): 1.83e-84: 252: 51.43
+	Xl
		993165 Q07CZ6_XENLA (1-558): 2.61e-87: 293: 21.28		AS1AA_XENLA (1-204): 2.01e-123: 348: 92.65
+	Gg
		1107997 CAF1B_CHICK (1-537): 1.72e-81: 277: 22.16		ASF1_CHICK (1-204): 2.31e-128: 361: 100.00
+	Hs
		1024612 CAF1B_HUMAN (1-522): 3.05e-81: 276: 23.23		ASF1A_HUMAN (1-204): 2.31e-128: 361: 100.00
+	Hs
		1024600 CAF1B_HUMAN (1-522): 3.05e-81: 276: 23.23		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Dm
		184546 HIRA_DROME (1-622): 1.36e-93: 322: 43.89		ASF1_DROME (1-203): 1.05e-97: 284: 56.88
+	Sc
		689846 HIR1_YEAST (1-862): 4.68e-99: 333: 20.45		ASF1_YEAST (1-168): 7.8e-88: 261: 54.76
+	Dm
		53064 A1Z898_DROME (1-737): 3.89e-84: 290: 18.26		ASF1_DROME (1-203): 1.05e-97: 284: 56.88
+	Sc
		689955 CAC2_YEAST (1-420): 7.29e-87: 289: 20.08		ASF1_YEAST (1-168): 7.8e-88: 261: 54.76
+	Hs
		1288338 SNR40_HUMAN (4-157): 7.3e-13: 73.4: 19.23		ASF1B_HUMAN (1-204): 9.25e-121: 342: 70.59
+	Sp
		251229 SLM9_SCHPO (2-366): 2e-31: 134: 23.99		ASF1_SCHPO (1-169): 1.83e-84: 252: 51.43
+	Sc
		689847 HIR2_YEAST (1-367): 4.2e-18: 91.8: 18.78		ASF1_YEAST (1-168): 7.8e-88: 261: 54.76
+	Sp
		144001 YEG3_SCHPO (171-501): 2.27e-12: 72.6: 13.58		ASF1_SCHPO (1-169): 1.83e-84: 252: 51.43