HitPredict

Interactor 1: F1RK46 (F1RK46)
histone acetyltransferase (EC 2.3.1.48)
Gene: CREBBP

Interactor 2: IRF3 (Q764M6)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Sus scrofa

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27334592
Identification Methods	comigration in non denaturing gel electrophoresis
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Creb_binding~IRF-3
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2440 Ss			1 419
+	Hs
		1056440 CBP_HUMAN (1-2440): 0: 1060: 94.89		IRF3_HUMAN (1-419): 0: 591: 77.91
+	Hs
		1039460 CBP_HUMAN (1-2440): 0: 1060: 94.89		IRF5_HUMAN (2-407): 1.3e-146: 427: 29.10
+	Hs
		971743 CBP_HUMAN (1-2440): 0: 1060: 94.89		IRF8_HUMAN (7-385): 7.27e-142: 413: 26.85
+	Hs
		998708 EP300_HUMAN (1-2414): 0: 864: 54.47		IRF3_HUMAN (1-419): 0: 591: 77.91
+	Hs
		1270761 CBP_HUMAN (1-2440): 0: 1060: 94.89		IRF7_HUMAN (4-380): 9.94e-111: 336: 25.81
+	Hs
		962717 CBP_HUMAN (1-2440): 0: 1060: 94.89		IRF9_HUMAN (7-386): 3.82e-98: 300: 24.26
+	Hs
		998733 EP300_HUMAN (1-2414): 0: 864: 54.47		IRF4_HUMAN (7-411): 8.34e-153: 441: 27.60
+	Hs
		998671 EP300_HUMAN (1-2414): 0: 864: 54.47		IRF5_HUMAN (2-407): 1.3e-146: 427: 29.10
+	Hs
		501074 CBP_HUMAN (1-2440): 0: 1060: 94.89		IRF1_HUMAN (1-207): 5.85e-49: 170: 25.23
+	Hs
		998953 EP300_HUMAN (1-2414): 0: 864: 54.47		IRF7_HUMAN (4-380): 9.94e-111: 336: 25.81
+	Hs
		536517 EP300_HUMAN (1-2414): 0: 864: 54.47		IRF2_HUMAN (1-156): 1.87e-49: 173: 27.22
+	Hs
		501043 EP300_HUMAN (1-2414): 0: 864: 54.47		IRF1_HUMAN (1-207): 5.85e-49: 170: 25.23
+	Mm
		70908 EP300_MOUSE (1833-2322): 6.36e-10: 67.1: 9.80		IRF3_MOUSE (1-419): 0: 528: 68.41
+	Hs
		1071078 CHD7_HUMAN (2005-2434): 2.4e-10: 68.7: 8.14		IRF4_HUMAN (7-411): 8.34e-153: 441: 27.60
+	Hs
		1071055 KMT2C_HUMAN (1854-2275): 4.18e-09: 64.7: 12.04		IRF4_HUMAN (7-411): 8.34e-153: 441: 27.60
+	Hs
		436004 CO1A2_HUMAN (1840-2227): 5.36e-17: 90.2: 13.08		IRF2_HUMAN (1-156): 1.87e-49: 173: 27.22
+	Hs
		436003 CO1A2_HUMAN (1840-2227): 5.36e-17: 90.2: 13.08		IRF1_HUMAN (1-207): 5.85e-49: 170: 25.23