HitPredict

Interactor 1: ARP4 (P80428)
Actin-related protein 4 (Actin-like protein ARP4) (Actin-like protein 4)
Gene: ARP4

Interactor 2: VPS72 (Q03388)
Vacuolar protein sorting-associated protein 72 (SWR complex protein 2)
Gene: VPS72

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	15610740, 16554755, 37968396, 14690608
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~YL1_C
Common GO terms	GO:0000785 - chromatin GO:0000812 - Swr1 complex GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription and 1 others more... GO:0042393 - histone binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 489 Sc			1 795
+	Sc
		887659 ACT_YEAST (301-488): 9.89e-73: 236: 27.51		VPS72_YEAST (1-795): 0: 966: 100.00
+	Sp
		1350728 ARP4_SCHPO (9-483): 2.86e-156: 452: 34.23		VPS72_SCHPO (14-305): 2.47e-36: 141: 19.18
+	Hs
		891791 ACTB_HUMAN (274-488): 4.21e-65: 216: 23.87		VPS72_HUMAN (16-304): 1.46e-46: 172: 20.76
+	Sp
		501587 ACT_SCHPO (274-488): 8.6e-62: 208: 24.23		VPS72_SCHPO (14-305): 2.47e-36: 141: 19.18
+	Dm
		54871 ACT6_DROME (274-488): 1.51e-63: 212: 24.32		A1ZA72_DROME (60-483): 1.16e-09: 64.6: 13.10
+	Hs
		331520 ACL6A_HUMAN (301-482): 7.4e-22: 99.8: 33.67		VPS72_HUMAN (16-304): 1.46e-46: 172: 20.76