Interactor 1: NLRP6 (P59044)
NACHT, LRR and PYD domains-containing protein 6 (Angiotensin II/vasopressin receptor) (PYRIN-containing APAF1-like protein 5)
Gene: NLRP6
Interactor 2: TCAM2 (Q86XR7)
TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4)
Gene: TICAM2
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.55 | 0.458 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37770465 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0035591 - signaling adaptor activity GO:2000494 - positive regulation of interleukin-18-mediated signaling pathway |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025