Interactor 1: HTRA4 (P83105)
Serine protease HTRA4 (EC 3.4.21.-) (High-temperature requirement factor A4)
Gene: HTRA4
Interactor 2: XIAP (P98170)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.81 | 0.50 | 0.637 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31036715, 31470122, 15201285 |
| Identification Methods | pull down, enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, protease assay, enzyme linked immunosorbent assay, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, protein cleavage, association, cleavage reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | - |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
