HitPredict

Interactor 1: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27507650, 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase, Pkinase~SAM_1
Common GO terms GO:0000165 - MAPK cascade
GO:0005737 - cytoplasm
GO:0098978 - glutamatergic synapse
GO:0099092 - postsynaptic density, intracellular component
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1323
Mm

1 1730
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Last updated: 15 Jul 2024