HitPredict

Interactor 1: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: EHMT1 (Q5DW34)
Histone-lysine N-methyltransferase EHMT1 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP) (GLP1) (Lysine N-methyltransferase 1D)
Gene: EHMT1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase, Ank_4~Pkinase
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1323 Mm			1 1296
+	Mm
		949433 TNIK_MOUSE (1-1323): 0: 1277: 100.00		EHMT2_MOUSE (119-1289): 0: 699: 45.72
+	Mm
		82720 TNIK_MOUSE (1-1323): 0: 1277: 100.00		CTTB2_MOUSE (262-1115): 4.96e-100: 353: 16.20
+	Mm
		103596 TNIK_MOUSE (1-1323): 0: 1277: 100.00		ANK3_MOUSE (682-1170): 4.89e-65: 245: 16.36
+	Hs
		1356406 TNIK_HUMAN (1-1323): 0: 1245: 95.15		ANR50_HUMAN (613-1152): 9.58e-69: 256: 17.37
+	Hs
		1021472 TNIK_HUMAN (1-1323): 0: 1245: 95.15		ANK3_HUMAN (710-1170): 2.53e-61: 234: 16.92
+	Hs
		257718 TNIK_HUMAN (1-1323): 0: 1245: 95.15		ANR17_HUMAN (796-1165): 3.46e-38: 159: 18.45
+	Mm
		949370 TNIK_MOUSE (1-1323): 0: 1277: 100.00		ANK2_MOUSE (4-707): 7.8e-14: 79: 9.66
+	Hs
		1264914 TNIK_HUMAN (1-1323): 0: 1245: 95.15		CTTB2_HUMAN (10-758): 2.91e-17: 90.4: 11.92
+	Hs
		965172 TNIK_HUMAN (1-1323): 0: 1245: 95.15		ANK2_HUMAN (9-570): 2.73e-10: 67.4: 11.91
+	Hs
		324853 M4K4_HUMAN (1-1323): 0: 1016: 62.17		CTTB2_HUMAN (10-758): 2.91e-17: 90.4: 11.92
+	Hs
		203675 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		SUV91_HUMAN (947-1265): 2.43e-89: 297: 30.31
+	Hs
		862065 MARK2_HUMAN (8-709): 1.53e-130: 423: 17.94		DAPK1_HUMAN (861-1122): 1.3e-32: 140: 20.15
+	Hs
		647851 MARK3_HUMAN (3-717): 6.96e-125: 406: 16.08		DAPK1_HUMAN (861-1122): 1.3e-32: 140: 20.15
+	Hs
		1264911 STK26_HUMAN (16-396): 9.79e-114: 364: 38.40		CTTB2_HUMAN (10-758): 2.91e-17: 90.4: 11.92
+	Hs
		1264921 STK24_HUMAN (20-400): 6.46e-113: 363: 37.86		CTTB2_HUMAN (10-758): 2.91e-17: 90.4: 11.92
+	Hs
		131594 STK25_HUMAN (20-433): 3.7e-113: 363: 37.17		CTTB2_HUMAN (10-758): 2.91e-17: 90.4: 11.92
+	Hs
		883501 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		RIPK4_HUMAN (561-771): 5.15e-12: 72.6: 15.81
+	Hs
		1027432 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		Q9H4D1_HUMAN (561-771): 7.68e-12: 72.2: 15.81
+	Hs
		1330871 STK26_HUMAN (16-396): 9.79e-114: 364: 38.40		Q9H4D1_HUMAN (561-771): 7.68e-12: 72.2: 15.81