HitPredict

Interactor 1: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: APC (Q61315)
Adenomatous polyposis coli protein (Protein APC) (mAPC)
Gene: APC

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28671696
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016055 - Wnt signaling pathway GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1323 Mm			1 2845
+	Mm
		949359 TNIK_MOUSE (1-1323): 0: 1277: 100.00		Q8BNP7_MOUSE (1-1056): 0: 1484: 100.00
+	Hs
		626177 MARK2_HUMAN (8-709): 1.53e-130: 423: 17.94		APC_HUMAN (1-2845): 0: 1266: 90.00
+	Hs
		92380 E9PC69_HUMAN (8-709): 5.54e-127: 413: 17.96		APC_HUMAN (1-2845): 0: 1266: 90.00
+	Hs
		159158 CSKP_HUMAN (22-702): 1.09e-122: 405: 15.80		APC_HUMAN (1-2845): 0: 1266: 90.00
+	Mm
		949370 TNIK_MOUSE (1-1323): 0: 1277: 100.00		ANK2_MOUSE (1768-2844): 1.55e-10: 69.5: 10.80
+	Hs
		1356429 TNIK_HUMAN (1-1323): 0: 1245: 95.15		PCLO_HUMAN (1022-2702): 5.62e-10: 67.9: 11.07
+	Hs
		1233564 MINK1_HUMAN (1-1323): 0: 1091: 63.94		SRRM2_HUMAN (1849-2844): 3.26e-11: 72: 11.27
+	Hs
		807705 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MAP1B_HUMAN (692-1903): 1.36e-12: 76.2: 8.33
+	Hs
		807708 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MAP1B_HUMAN (692-1903): 1.36e-12: 76.2: 8.33
+	Hs
		1023059 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MAP1S_HUMAN (2396-2833): 6.61e-10: 67.1: 12.98
+	Hs
		1027383 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MAP1S_HUMAN (2396-2833): 6.61e-10: 67.1: 12.98