HitPredict

Interactor 1: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: AKAP9 (Q70FJ1)
A-kinase anchor protein 9 (AKAP-9) (Protein kinase A-anchoring protein 9) (PRKA9)
Gene: AKAP9

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1323 Mm			1 3797
+	Hs
		1307588 TNIK_HUMAN (1-1323): 0: 1245: 95.15		AKAP9_HUMAN (1-3797): 0: 764: 63.59
+	Mm
		93424 TNIK_MOUSE (1-1323): 0: 1277: 100.00		E9Q3P4_MOUSE (1278-3693): 7.65e-68: 259: 10.27
+	Mm
		949273 TNIK_MOUSE (1-1323): 0: 1277: 100.00		Q155P7_MOUSE (1278-3693): 1.06e-67: 258: 10.31
+	Hs
		1034641 TNIK_HUMAN (1-1323): 0: 1245: 95.15		GOGA4_HUMAN (2-1247): 1.95e-41: 172: 11.12
+	Mm
		949333 TNIK_MOUSE (1-1323): 0: 1277: 100.00		SYNE1_MOUSE (1-2588): 7.37e-26: 120: 9.15
+	Mm
		949395 TNIK_MOUSE (1-1323): 0: 1277: 100.00		DYST_MOUSE (1577-3548): 1.19e-22: 110: 11.26
+	Hs
		974168 TNIK_HUMAN (1-1323): 0: 1245: 95.15		DYST_HUMAN (1553-3548): 1.96e-20: 102: 10.81
+	Mm
		949400 TNIK_MOUSE (1-1323): 0: 1277: 100.00		MYO5A_MOUSE (445-973): 1.48e-10: 69.9: 15.48
+	Mm
		823531 TNIK_MOUSE (1-1323): 0: 1277: 100.00		CTRO_MOUSE (7-501): 7.17e-09: 64.5: 14.86
+	Hs
		1244144 TNIK_HUMAN (1-1323): 0: 1245: 95.15		SYNE1_HUMAN (1571-3643): 2.72e-18: 95.9: 9.27
+	Hs
		159258 CSKP_HUMAN (22-702): 1.09e-122: 405: 15.80		AKAP9_HUMAN (1-3797): 0: 764: 63.59
+	Mm
		956963 M4K4_MOUSE (1-1323): 0: 992: 59.97		CE290_MOUSE (1-1294): 1.81e-29: 132: 10.11
+	Hs
		1344754 SNRK_HUMAN (20-800): 1.21e-124: 406: 15.16		MYH2_HUMAN (2710-3702): 5.49e-34: 147: 11.29
+	Hs
		1313528 SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75		CP250_HUMAN (1-880): 5.73e-27: 124: 10.29
+	Hs
		728513 SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75		MYH11_HUMAN (3-545): 3.77e-22: 108: 11.19
+	Mm
		251106 CSKP_MOUSE (22-702): 1.11e-122: 405: 15.80		DYST_MOUSE (1577-3548): 1.19e-22: 110: 11.26
+	Hs
		522572 SNRK_HUMAN (20-800): 1.21e-124: 406: 15.16		MYH1_HUMAN (3217-3711): 1.53e-18: 96.3: 12.45
+	Hs
		1268074 MARK4_HUMAN (7-683): 5.7e-121: 396: 19.91		MY18A_HUMAN (2905-3478): 1.79e-10: 69.9: 19.62
+	Hs
		551616 AKT1_HUMAN (3-358): 1.62e-122: 390: 21.08		DESP_HUMAN (2160-3346): 3.43e-12: 75.3: 16.25
+	Hs
		682219 AKT2_HUMAN (3-358): 1.46e-124: 396: 22.49		MYO5A_HUMAN (445-973): 6.08e-10: 68: 16.49