HitPredict

Interactor 1: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: MYOME (Q80YT7)
Myomegalin (Phosphodiesterase 4D-interacting protein)
Gene: Pde4dip

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1323 Mm			1 2224
+	Hs
		1138340 TNIK_HUMAN (1-1323): 0: 1245: 95.15		MYOME_HUMAN (1-2224): 5.46e-171: 584: 73.35
+	Mm
		1194559 MINK1_MOUSE (1-1323): 0: 1095: 64.51		MYOME_MOUSE (1-2224): 0: 695: 100.00
+	Mm
		956966 M4K4_MOUSE (1-1323): 0: 992: 59.97		MYOME_MOUSE (1-2224): 0: 695: 100.00
+	Mm
		93424 TNIK_MOUSE (1-1323): 0: 1277: 100.00		E9Q3P4_MOUSE (661-2214): 1.37e-31: 138: 8.85
+	Mm
		949273 TNIK_MOUSE (1-1323): 0: 1277: 100.00		Q155P7_MOUSE (661-2214): 1.51e-31: 138: 8.85
+	Hs
		1034641 TNIK_HUMAN (1-1323): 0: 1245: 95.15		GOGA4_HUMAN (2-1093): 6.72e-38: 159: 11.34
+	Hs
		1313528 SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75		CP250_HUMAN (63-2186): 3.42e-78: 291: 10.78
+	Hs
		728513 SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75		MYH11_HUMAN (1159-2211): 1.5e-38: 161: 9.81
+	Hs
		725242 SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75		MYH10_HUMAN (1220-2207): 2.37e-32: 140: 8.68
+	Hs
		725010 SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75		MYH9_HUMAN (1285-2194): 5.31e-30: 133: 9.43
+	Hs
		725223 MARK4_HUMAN (7-683): 5.7e-121: 396: 19.91		MYH10_HUMAN (1220-2207): 2.37e-32: 140: 8.68
+	Hs
		528369 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH6_HUMAN (1159-2210): 2.56e-34: 147: 9.60
+	Hs
		724967 MARK4_HUMAN (7-683): 5.7e-121: 396: 19.91		MYH9_HUMAN (1285-2194): 5.31e-30: 133: 9.43
+	Hs
		681696 AKT1_HUMAN (3-358): 1.62e-122: 390: 21.08		MYH9_HUMAN (1285-2194): 5.31e-30: 133: 9.43
+	Hs
		528408 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH8_HUMAN (1269-2207): 3.57e-32: 140: 9.45
+	Hs
		1344754 SNRK_HUMAN (20-800): 1.21e-124: 406: 15.16		MYH2_HUMAN (1574-2192): 8.05e-15: 83: 10.43
+	Hs
		522572 SNRK_HUMAN (20-800): 1.21e-124: 406: 15.16		MYH1_HUMAN (1574-2192): 8.05e-15: 83: 10.90
+	Hs
		522545 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH1_HUMAN (1574-2192): 8.05e-15: 83: 10.90
+	Hs
		502911 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH3_HUMAN (832-1506): 9.14e-11: 69.9: 11.29
+	Hs
		522609 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH7_HUMAN (6-357): 7.79e-10: 66.9: 11.60