HitPredict

Interactor 1: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: MYO5A (Q99104)
Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle)
Gene: MYO5A

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0055037 - recycling endosome GO:0098978 - glutamatergic synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1323 Mm			1 1853
+	Hs
		682219 AKT2_HUMAN (3-358): 1.46e-124: 396: 22.49		MYO5A_HUMAN (1-1853): 0: 1213: 92.62
+	Hs
		725010 SIK2_HUMAN (15-898): 5.45e-130: 425: 13.75		MYH9_HUMAN (835-1488): 7.31e-29: 129: 15.26
+	Hs
		724967 MARK4_HUMAN (7-683): 5.7e-121: 396: 19.91		MYH9_HUMAN (835-1488): 7.31e-29: 129: 15.26
+	Hs
		681696 AKT1_HUMAN (3-358): 1.62e-122: 390: 21.08		MYH9_HUMAN (835-1488): 7.31e-29: 129: 15.26
+	Hs
		1344754 SNRK_HUMAN (20-800): 1.21e-124: 406: 15.16		MYH2_HUMAN (712-1316): 3.16e-23: 110: 12.62
+	Hs
		528408 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH8_HUMAN (713-1411): 6.03e-30: 132: 10.17
+	Hs
		528409 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MYH8_HUMAN (713-1411): 6.03e-30: 132: 10.17
+	Hs
		528369 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH6_HUMAN (775-1496): 8.25e-27: 122: 14.49
+	Hs
		528371 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MYH6_HUMAN (775-1496): 8.25e-27: 122: 14.49
+	Hs
		522572 SNRK_HUMAN (20-800): 1.21e-124: 406: 15.16		MYH1_HUMAN (711-1233): 1.53e-17: 92.1: 13.37
+	Hs
		1023137 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH2_HUMAN (712-1316): 3.16e-23: 110: 12.62
+	Hs
		1027452 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MYH2_HUMAN (712-1316): 3.16e-23: 110: 12.62
+	Hs
		522545 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH1_HUMAN (711-1233): 1.53e-17: 92.1: 13.37
+	Hs
		522546 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MYH1_HUMAN (711-1233): 1.53e-17: 92.1: 13.37
+	Hs
		502911 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH3_HUMAN (823-1171): 1.46e-15: 85.5: 16.76
+	At
		98846 KIN10_ARATH (19-478): 3.17e-126: 402: 18.10		MYO17_ARATH (1501-1780): 5.14e-09: 63.6: 8.83
+	Hs
		502912 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MYH3_HUMAN (823-1171): 1.46e-15: 85.5: 16.76
+	Hs
		522609 STK4_HUMAN (5-470): 3.93e-119: 382: 32.59		MYH7_HUMAN (1511-1816): 4.41e-09: 63.9: 10.42
+	Hs
		522610 STK3_HUMAN (4-496): 1.39e-117: 377: 30.12		MYH7_HUMAN (1511-1816): 4.41e-09: 63.9: 10.42