HitPredict

Interactor 1: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Interactor 2: SGO1 (Q5FBB7)
Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1)
Gene: SGO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.661

Property	Details
Experiments	24981860, 18716626, 21346195
Identification Methods	affinity chromatography technology, two hybrid, isothermal titration calorimetry, x-ray crystallography
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000775 - chromosome, centromeric region GO:0005654 - nucleoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 185 Hs			1 561
+	Hs
		1027030 CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49		SGO1_HUMAN (1-561): 0: 1046: 100.00
+	Hs
		800408 CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45		SGO1_HUMAN (1-561): 0: 1046: 100.00