HitPredict

Interactor 1: CBX1 (P83917)
Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein)
Gene: CBX1

Interactor 2: TIF1B (Q62318)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-A-interacting protein) (KRIP-1) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: Trim28

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.936

The method score is based on:

Property Details
Experiments 10562550, 29795351, 15342492, 17381543, 10747027
Identification Methods pull down, affinity chromatography technology, two hybrid, fluorescent resonance energy transfer, enzymatic study, competition binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~PHD
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006325 - chromatin organization
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 185
Mm

1 834
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024