HitPredict

Interactor 1: SMAD3 (P84022)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)
Gene: SMAD3

Interactor 2: SVEP1 (Q4LDE5)
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (CCP module-containing protein 22) (Polydom) (Selectin-like osteoblast-derived protein) (SEL-OB) (Serologically defined breast cancer antigen NY-BR-38)
Gene: SVEP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15231748
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 3571
+	Hs
		171403 SMAD9_HUMAN (1-425): 0: 559: 58.62		SVEP1_HUMAN (1-3571): 0: 1538: 100.00
+	Hs
		804201 SMAD3_HUMAN (1-425): 0: 636: 100.00		NOTC1_HUMAN (227-1315): 1.13e-16: 90.2: 8.90
+	Hs
		950250 SMAD3_HUMAN (1-425): 0: 636: 100.00		CSMD1_HUMAN (378-1023): 4.23e-14: 81.7: 9.45
+	Hs
		950260 SMAD3_HUMAN (1-425): 0: 636: 100.00		NOTC4_HUMAN (252-1177): 7.05e-11: 71: 10.56
+	Hs
		441720 SMAD3_HUMAN (1-425): 0: 636: 100.00		CFAH_HUMAN (222-755): 1.08e-10: 70.2: 11.04
+	Hs
		1078639 SMAD2_HUMAN (1-425): 0: 589: 83.73		NOTC4_HUMAN (252-1177): 7.05e-11: 71: 10.56
+	Hs
		980382 SMAD1_HUMAN (1-425): 0: 559: 60.09		NOTC2_HUMAN (227-1256): 1.96e-17: 92.5: 11.01
+	Hs
		171369 SMAD9_HUMAN (1-425): 0: 559: 58.62		NOTC1_HUMAN (227-1315): 1.13e-16: 90.2: 8.90
+	Hs
		1035564 SMAD4_HUMAN (23-414): 1.55e-117: 355: 33.21		NOTC4_HUMAN (252-1177): 7.05e-11: 71: 10.56