HitPredict

Interactor 1: ARF1 (P84077)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Interactor 2: GGA3 (Q9NZ52)
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)
Gene: GGA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.891

Property	Details
Experiments	11950392, 28100775, 11301005, 10747089
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Arf~GGA_N-GAT
Common GO terms	GO:0006886 - intracellular protein transport GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 723
+	Hs
		913149 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00
+	Hs
		897409 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		GGA3_HUMAN (1-723): 3.49e-148: 451: 100.00
+	Mm
		950589 ARF1_MOUSE (1-181): 5.85e-68: 206: 100.00		GGA3_MOUSE (1-723): 5.14e-130: 403: 81.27
+	Rn
		88618 ARF6_RAT (5-179): 2.19e-73: 219: 68.00		D3ZHG8_RAT (1-723): 6.55e-121: 378: 67.08
+	Rn
		88617 ARF3_RAT (1-181): 6.38e-68: 206: 96.13		D3ZHG8_RAT (1-723): 6.55e-121: 378: 67.08
+	Rn
		88619 ARF1_RAT (1-181): 5.85e-68: 206: 100.00		D3ZHG8_RAT (1-723): 6.55e-121: 378: 67.08
+	Hs
		913175 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		950740 ARF5_HUMAN (1-180): 2.95e-68: 207: 80.56		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		897416 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		950575 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		277049 ARF5_HUMAN (1-180): 2.95e-68: 207: 80.56		STAM2_HUMAN (1-480): 4.23e-79: 264: 16.95
+	Dm
		778418 ARF6_DROME (5-178): 4.75e-72: 216: 68.39		Q9W329_DROME (9-705): 8.66e-69: 240: 22.06
+	Sc
		580871 ARF2_YEAST (1-180): 1.01e-65: 201: 77.22		GGA1_YEAST (2-425): 1.01e-68: 237: 21.28
+	Sc
		580855 ARF2_YEAST (1-180): 1.01e-65: 201: 77.22		GGA2_YEAST (2-437): 2.07e-66: 231: 21.70
+	Hs
		212615 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		AP1G1_HUMAN (503-720): 2.89e-51: 193: 26.96
+	Hs
		212618 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		AP1G1_HUMAN (503-720): 2.89e-51: 193: 26.96
+	Hs
		913174 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83
+	Hs
		574772 ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83
+	Hs
		897415 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83
+	Hs
		950574 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83