HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 694
+	Hs
		925254 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		900445 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Mm
		892732 CDC42_MOUSE (1-191): 1.3e-78: 234: 60.73		DOC10_MOUSE (6-571): 1e-123: 408: 15.09
+	Hs
		925588 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		DOCK9_HUMAN (3-556): 1.29e-117: 390: 14.81
+	Hs
		951301 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		DOCK9_HUMAN (3-556): 1.29e-117: 390: 14.81
+	Hs
		925332 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		DOC11_HUMAN (3-563): 1.15e-114: 381: 13.19
+	Mm
		101404 CDC42_MOUSE (1-191): 1.3e-78: 234: 60.73		F8VPN7_MOUSE (3-556): 5.37e-117: 388: 14.46
+	Hs
		894099 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		DOC11_HUMAN (3-563): 1.15e-114: 381: 13.19
+	Mm
		57052 CDC42_MOUSE (1-191): 1.3e-78: 234: 60.73		DOC11_MOUSE (3-563): 5.98e-114: 379: 12.67
+	Hs
		925629 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PKHA5_HUMAN (5-476): 6.15e-67: 240: 13.00
+	Hs
		951352 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		PKHA5_HUMAN (5-476): 6.15e-67: 240: 13.00
+	Hs
		900922 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		PKHA5_HUMAN (5-476): 6.15e-67: 240: 13.00
+	Hs
		925632 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PKHA1_HUMAN (6-156): 1.25e-32: 132: 25.49
+	Hs
		951355 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		PKHA1_HUMAN (6-156): 1.25e-32: 132: 25.49
+	Hs
		900925 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		PKHA1_HUMAN (6-156): 1.25e-32: 132: 25.49
+	Hs
		925612 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		DEFI6_HUMAN (4-111): 7.29e-15: 80.2: 21.30
+	Hs
		900898 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		DEFI6_HUMAN (4-111): 7.29e-15: 80.2: 21.30
+	Hs
		297823 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		K0754_HUMAN (339-656): 1.08e-09: 64.4: 11.22
+	Hs
		297827 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		K0754_HUMAN (339-656): 1.08e-09: 64.4: 11.22
+	Hs
		297820 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		K0754_HUMAN (339-656): 1.08e-09: 64.4: 11.22