HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: M3K11 (Q16584)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)
Gene: MAP3K11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12376551
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 847
+	Hs
		925309 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		M3K11_HUMAN (1-847): 0: 649: 100.00
+	Hs
		545402 RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35		M3K11_HUMAN (1-847): 0: 649: 100.00
+	Hs
		894058 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		M3K11_HUMAN (1-847): 0: 649: 100.00
+	Hs
		892395 RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88		M3K11_HUMAN (1-847): 0: 649: 100.00
+	Hs
		925212 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		M3K10_HUMAN (38-840): 6.34e-155: 479: 44.59
+	Hs
		893917 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		M3K10_HUMAN (38-840): 6.34e-155: 479: 44.59
+	Hs
		892422 RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88		M3K21_HUMAN (45-830): 8.33e-141: 445: 46.01
+	Dm
		776899 RAC1_DROME (1-191): 5.32e-79: 235: 67.71		M3KSL_DROME (43-633): 6.46e-124: 403: 43.21
+	Dm
		776934 CDC42_DROME (1-191): 1.78e-77: 231: 60.21		M3KSL_DROME (43-633): 6.46e-124: 403: 43.21
+	Dm
		816383 RHO1_DROME (5-191): 6.13e-75: 225: 56.68		M3KSL_DROME (43-633): 6.46e-124: 403: 43.21
+	Hs
		199540 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		M3K13_HUMAN (85-781): 7.92e-121: 390: 25.91
+	Hs
		893935 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		ACK1_HUMAN (61-847): 1.02e-118: 386: 20.77
+	Rn
		1137281 CDC42_RAT (1-191): 1.3e-78: 234: 60.73		ACK1_RAT (55-847): 5.53e-116: 379: 21.52
+	Dm
		87957 RHO1_DROME (5-191): 6.13e-75: 225: 56.68		D3DMF6_DROME (110-683): 8.43e-119: 384: 27.00
+	Hs
		894512 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		M3K20_HUMAN (114-461): 3.54e-113: 365: 37.11
+	Hs
		789109 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		FRK_HUMAN (113-377): 1.3e-100: 323: 34.06