HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: PI51A (Q99755)
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)
Gene: PIP5K1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030036 - actin cytoskeleton organization GO:0060326 - cell chemotaxis and 1 others more... GO:0090630 - activation of GTPase activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 562
+	Hs
		925559 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PI51A_HUMAN (18-562): 0: 815: 100.00
+	Hs
		545583 RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35		PI51A_HUMAN (18-562): 0: 815: 100.00
+	Hs
		892558 RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88		PI51A_HUMAN (18-562): 0: 815: 100.00
+	Hs
		564659 RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84		PI51A_HUMAN (18-562): 0: 815: 100.00
+	Hs
		231388 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PI51C_HUMAN (50-539): 0: 624: 69.03
+	At
		1105127 RAC3_ARATH (2-180): 7.36e-92: 268: 56.98		PI5KB_ARATH (117-451): 2.82e-110: 336: 26.74
+	Hs
		925747 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		FYV1_HUMAN (51-331): 3.16e-64: 230: 20.94