HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: GOPC (Q9HD26)
Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST)
Gene: GOPC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 462
+	Hs
		900727 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		PAR3L_HUMAN (10-462): 7.64e-47: 176: 15.23
+	Mm
		925797 RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88		DLG4_MOUSE (119-452): 1.11e-36: 145: 14.21
+	Hs
		158270 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		LIN7A_HUMAN (280-390): 1.23e-35: 133: 37.84
+	Hs
		925250 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		SNTB2_HUMAN (282-372): 4.04e-33: 133: 45.06
+	Hs
		950970 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		SNTB2_HUMAN (282-372): 4.04e-33: 133: 45.06
+	Hs
		893970 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		SNTB2_HUMAN (282-372): 4.04e-33: 133: 45.06
+	Hs
		900440 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		SNTB2_HUMAN (282-372): 4.04e-33: 133: 45.06
+	Hs
		925236 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		925463 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PARD3_HUMAN (223-458): 8e-22: 100: 19.84
+	Hs
		951182 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		PARD3_HUMAN (223-458): 8e-22: 100: 19.84
+	Hs
		893945 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		900421 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		PTN13_HUMAN (47-459): 1.31e-22: 103: 13.74
+	Hs
		900726 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		PARD3_HUMAN (223-458): 8e-22: 100: 19.84
+	Hs
		951207 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		DLG3_HUMAN (13-264): 5.95e-15: 79.3: 10.24
+	Hs
		925457 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		DLG5_HUMAN (37-370): 1.51e-13: 75.4: 15.88
+	Hs
		951180 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		DLG5_HUMAN (37-370): 1.51e-13: 75.4: 15.88
+	Hs
		900762 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		DLG3_HUMAN (13-264): 5.95e-15: 79.3: 10.24
+	Hs
		900722 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		DLG5_HUMAN (37-370): 1.51e-13: 75.4: 15.88
+	Hs
		900710 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		INADL_HUMAN (12-452): 3.38e-13: 74.3: 13.78
+	Hs
		901012 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		ZO2_HUMAN (271-444): 3.18e-09: 61.4: 18.23