HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: ELAV2 (Q12926)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene: ELAVL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 164 Hs			1 359
+	Hs
		992743 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		266976 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		1020249 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		516484 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		853881 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87
+	Hs
		516466 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516478 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		266904 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516425 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516495 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516339 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		668339 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Hs
		266998 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27
+	Hs
		668348 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Hs
		516371 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Hs
		703388 CSTF2_HUMAN (10-110): 1.87e-25: 103: 25.47		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90
+	Mm
		936689 SRSF7_MOUSE (7-115): 1.47e-26: 102: 60.55		ELAV1_MOUSE (24-120): 1.54e-17: 84.3: 29.90
+	Mm
		936671 SRSF3_MOUSE (1-164): 6.39e-27: 100: 100.00		ELAV1_MOUSE (24-120): 1.54e-17: 84.3: 29.90
+	Hs
		1031344 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90