HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: ERBB4 (Q15303)
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]
Gene: ERBB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0050811 - GABA receptor binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 1308
+	Hs
		410745 GBRL2_HUMAN (1-117): 1.09e-58: 178: 100.00		ERBB2_HUMAN (25-1274): 0: 1094: 45.98
+	Hs
		411044 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		ERBB2_HUMAN (25-1274): 0: 1094: 45.98
+	Hs
		641543 GBRL2_HUMAN (1-117): 1.09e-58: 178: 100.00		ERBB3_HUMAN (1-1258): 0: 1083: 47.41
+	Hs
		641672 GBRL1_HUMAN (1-116): 7.93e-56: 170: 61.21		ERBB3_HUMAN (1-1258): 0: 1083: 47.41
+	Hs
		363064 GBRL2_HUMAN (1-117): 1.09e-58: 178: 100.00		EGFR_HUMAN (20-1286): 0: 1028: 48.70
+	Hs
		363853 MLP3A_HUMAN (5-117): 2.02e-45: 144: 41.74		EGFR_HUMAN (20-1286): 0: 1028: 48.70