HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	27705803, 33961781, 36089195, 14718166, 19410545
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 425
+	Hs
		934696 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Mm
		935452 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		RBBP4_MOUSE (1-425): 4.3e-124: 367: 100.00
+	Mm
		952746 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		RBBP4_MOUSE (1-425): 4.3e-124: 367: 100.00
+	Hs
		997742 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Hs
		934809 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		952365 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		1083261 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Mm
		935449 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		Q3UJI2_MOUSE (1-425): 6.93e-114: 341: 88.97
+	Mm
		952742 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		Q3UJI2_MOUSE (1-425): 6.93e-114: 341: 88.97
+	Mm
		952255 H32_MOUSE (1-136): 5.32e-59: 180: 97.06		Q3UJI2_MOUSE (1-425): 6.93e-114: 341: 88.97
+	Hs
		267767 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		TAF5L_HUMAN (26-422): 3e-74: 244: 22.20
+	Hs
		935208 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TBL1R_HUMAN (109-424): 2.86e-60: 205: 16.52
+	Hs
		934796 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23
+	Hs
		952358 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23
+	Hs
		1074789 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23
+	Hs
		903117 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		903128 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		903260 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		935175 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56
+	Hs
		934971 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		DAW1_HUMAN (9-106): 2.42e-20: 94.1: 8.74