HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: PIAS4 (Q8N2W9)
E3 SUMO-protein ligase PIAS4 (EC 2.3.2.27) (PIASy) (Protein inhibitor of activated STAT protein 4) (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma)
Gene: PIAS4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 510
+	Hs
		934975 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		PIAS4_HUMAN (1-510): 0: 670: 100.00
+	Hs
		828297 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		PIAS4_HUMAN (1-510): 0: 670: 100.00
+	Hs
		278047 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		PIAS1_HUMAN (3-508): 2.66e-180: 522: 46.42
+	Hs
		278050 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		PIAS1_HUMAN (3-508): 2.66e-180: 522: 46.42
+	Hs
		278260 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		PIAS2_HUMAN (3-504): 9.32e-180: 520: 44.74
+	Hs
		278117 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		PIAS1_HUMAN (3-508): 2.66e-180: 522: 46.42
+	Hs
		278265 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		PIAS2_HUMAN (3-504): 9.32e-180: 520: 44.74
+	Hs
		277992 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		PIAS1_HUMAN (3-508): 2.66e-180: 522: 46.42
+	Hs
		278248 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		PIAS2_HUMAN (3-504): 9.32e-180: 520: 44.74
+	Os
		1001558 H33_ORYSJ (1-136): 3.83e-60: 183: 95.59		SIZ1_ORYSJ (1-460): 4.78e-75: 255: 19.37
+	Sc
		730913 CENPA_YEAST (18-134): 3.39e-40: 135: 56.67		SIZ1_YEAST (4-407): 3.42e-59: 212: 21.35