HitPredict

Interactor 1: BRO1 (F4HXZ1)
Vacuolar-sorting protein BRO1 (BRO domain-containing protein 1) (AtBRO1)
Gene: BRO1

Interactor 2: VP322 (Q9SZE4)
Vacuolar protein sorting-associated protein 32 homolog 2 (AtVPS32-2) (Charged multivesicular body protein 4 homolog 2) (ESCRT-III complex subunit VPS32 homolog 2)
Gene: VPS32.2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	22639582, 21798944
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005771 - multivesicular body
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 846 At			1 219
+	At
		95242 BRO1_ARATH (1-846): 1e-178: 538: 100.00		VP321_ARATH (1-219): 6.2e-37: 130: 79.91
+	Hs
		1260376 PDC6I_HUMAN (10-846): 5.22e-152: 469: 24.43		CHM4C_HUMAN (8-218): 3.39e-39: 136: 33.79
+	Dm
		1249814 Q9VB05_DROME (10-846): 8.85e-151: 465: 25.55		CHM4_DROME (1-218): 1.33e-40: 139: 27.93
+	Hs
		1260401 PDC6I_HUMAN (10-846): 5.22e-152: 469: 24.43		CHM4B_HUMAN (13-218): 4.66e-38: 133: 37.86
+	Hs
		1260391 PDC6I_HUMAN (10-846): 5.22e-152: 469: 24.43		CHM4A_HUMAN (2-217): 1e-33: 122: 35.32
+	Hs
		1330347 PTN23_HUMAN (9-842): 4.29e-140: 455: 22.36		CHM4B_HUMAN (13-218): 4.66e-38: 133: 37.86
+	Dm
		1249821 Q9VUH6_DROME (10-845): 1.95e-104: 357: 21.26		CHM4_DROME (1-218): 1.33e-40: 139: 27.93
+	Sc
		764862 BRO1_YEAST (10-809): 5e-94: 315: 18.04		SNF7_YEAST (1-208): 2.43e-32: 119: 27.70
+	Sc
		764903 PALA_YEAST (10-719): 3.85e-92: 306: 20.86		SNF7_YEAST (1-208): 2.43e-32: 119: 27.70
+	Sc
		820024 BRO1_YEAST (10-809): 5e-94: 315: 18.04		VPS20_YEAST (8-219): 5.68e-28: 107: 17.97
+	Hs
		1138944 BROX_HUMAN (26-357): 7.31e-64: 222: 18.70		CHM4C_HUMAN (8-218): 3.39e-39: 136: 33.79
+	Hs
		1138947 BROX_HUMAN (26-357): 7.31e-64: 222: 18.70		CHM4B_HUMAN (13-218): 4.66e-38: 133: 37.86
+	Hs
		1138950 BROX_HUMAN (26-357): 7.31e-64: 222: 18.70		CHMP5_HUMAN (2-193): 2.04e-35: 126: 30.20
+	Hs
		1138946 BROX_HUMAN (26-357): 7.31e-64: 222: 18.70		CHM4A_HUMAN (2-217): 1e-33: 122: 35.32