HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 536
+	Hs
		934809 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16
+	Mm
		935449 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		Q3UJI2_MOUSE (105-535): 1.53e-75: 246: 14.60
+	Hs
		952365 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16
+	Hs
		1083261 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16
+	Mm
		952742 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		Q3UJI2_MOUSE (105-535): 1.53e-75: 246: 14.60
+	Mm
		952255 H32_MOUSE (1-136): 5.32e-59: 180: 97.06		Q3UJI2_MOUSE (105-535): 1.53e-75: 246: 14.60
+	Hs
		148078 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44
+	Hs
		792992 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63
+	Hs
		934971 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		DAW1_HUMAN (48-340): 1.54e-50: 180: 9.54
+	Hs
		903117 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		903128 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		903260 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		935208 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TBL1R_HUMAN (250-526): 3.44e-47: 173: 12.46
+	Hs
		934696 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RBBP4_HUMAN (320-526): 6.81e-34: 134: 15.81
+	Mm
		935452 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		RBBP4_MOUSE (320-526): 6.81e-34: 134: 15.81
+	Hs
		952294 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RBBP4_HUMAN (320-526): 6.81e-34: 134: 15.81
+	Mm
		952746 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		RBBP4_MOUSE (320-526): 6.81e-34: 134: 15.81
+	Hs
		997742 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		RBBP4_HUMAN (320-526): 6.81e-34: 134: 15.81
+	Mm
		952258 H32_MOUSE (1-136): 5.32e-59: 180: 97.06		RBBP4_MOUSE (320-526): 6.81e-34: 134: 15.81
+	Hs
		952498 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		DC2I1_HUMAN (63-496): 4.07e-27: 118: 19.05