HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~zf-RING_6
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 777
+	Hs
		935164 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		934710 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ANK3_HUMAN (268-703): 3.36e-72: 260: 14.86
+	Hs
		934668 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ANK2_HUMAN (104-622): 2.47e-71: 257: 14.31
+	Hs
		965127 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		ANK2_HUMAN (104-622): 2.47e-71: 257: 14.31
+	Hs
		935156 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MPP8_HUMAN (119-549): 1.23e-51: 195: 15.51
+	Hs
		952579 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MPP8_HUMAN (119-549): 1.23e-51: 195: 15.51
+	Hs
		952423 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		BCOR_HUMAN (152-543): 1.16e-44: 176: 23.93
+	Hs
		828275 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		ANR11_HUMAN (280-544): 1.17e-42: 170: 25.74
+	Hs
		935114 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TONSL_HUMAN (423-532): 1.15e-20: 99.8: 46.90
+	Hs
		952547 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		TONSL_HUMAN (423-532): 1.15e-20: 99.8: 46.90
+	Hs
		1086274 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		TONSL_HUMAN (423-532): 1.15e-20: 99.8: 46.90
+	Hs
		1174629 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		TONSL_HUMAN (423-532): 1.15e-20: 99.8: 46.90