HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 350
+	Hs
		935201 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00
+	Hs
		1086305 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00
+	Hs
		717680 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		717875 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		935183 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		PCGF1_HUMAN (119-347): 3.16e-60: 196: 34.91
+	Hs
		952593 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		PCGF1_HUMAN (119-347): 3.16e-60: 196: 34.91
+	Hs
		717557 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		584928 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RO52_HUMAN (121-311): 4.15e-35: 135: 17.79
+	Hs
		935154 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		952576 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		952625 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RNF41_HUMAN (127-329): 3.09e-32: 124: 17.54
+	Hs
		1086286 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		282622 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RNF8_HUMAN (74-217): 4.44e-28: 115: 24.16
+	Hs
		934691 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		RING1_HUMAN (109-211): 1.44e-25: 108: 25.96
+	Hs
		952292 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		RING1_HUMAN (109-211): 1.44e-25: 108: 25.96
+	Hs
		987976 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		RING1_HUMAN (109-211): 1.44e-25: 108: 25.96
+	Hs
		828356 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		828206 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		RING1_HUMAN (109-211): 1.44e-25: 108: 25.96