HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: MCM2 (P97310)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20211137
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~MCM2_N
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 904
+	Hs
		832357 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM2_HUMAN (1-904): 0: 1033: 95.58
+	Hs
		832369 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM2_HUMAN (1-904): 0: 1033: 95.58
+	Hs
		832495 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		MCM2_HUMAN (1-904): 0: 1033: 95.58
+	Mm
		935446 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		MCM2_MOUSE (1-904): 0: 1016: 100.00
+	Mm
		952250 H32_MOUSE (1-136): 5.32e-59: 180: 97.06		MCM2_MOUSE (1-904): 0: 1016: 100.00
+	Hs
		708415 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM4_HUMAN (21-869): 0: 793: 28.09
+	Hs
		708421 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM4_HUMAN (21-869): 0: 793: 28.09
+	Hs
		708603 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM5_HUMAN (168-900): 0: 708: 29.24
+	Hs
		708605 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM5_HUMAN (168-900): 0: 708: 29.24
+	Hs
		708661 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		MCM5_HUMAN (168-900): 0: 708: 29.24
+	Mm
		935450 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		Q3V122_MOUSE (188-886): 0: 664: 27.67
+	Mm
		952743 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		Q3V122_MOUSE (188-886): 0: 664: 27.67
+	Hs
		627235 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM3_HUMAN (193-897): 0: 656: 28.67
+	Hs
		708861 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM7_HUMAN (188-886): 0: 656: 27.41
+	Mm
		935447 H31_MOUSE (1-136): 3.08e-60: 183: 96.32		MCM6_MOUSE (186-827): 0: 656: 30.44
+	Hs
		708865 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM7_HUMAN (188-886): 0: 656: 27.41
+	Mm
		952737 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		MCM6_MOUSE (186-827): 0: 656: 30.44
+	Hs
		708932 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		MCM7_HUMAN (188-886): 0: 656: 27.41
+	Hs
		934761 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MCM6_HUMAN (179-824): 0: 653: 30.69
+	Hs
		952336 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MCM6_HUMAN (179-824): 0: 653: 30.69