HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: HIRA (Q61666)
Protein HIRA (TUP1-like enhancer of split protein 1)
Gene: HIRA

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.655

Property	Details
Experiments	9731536, 20211137, 24074864
Identification Methods	two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0001649 - osteoblast differentiation GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0042692 - muscle cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 1015
+	Hs
		867850 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HIRA_HUMAN (1-1015): 0: 798: 95.48
+	Hs
		867853 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HIRA_HUMAN (1-1015): 0: 798: 95.48
+	Hs
		867878 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		HIRA_HUMAN (1-1015): 0: 798: 95.48
+	At
		886471 H33_ARATH (1-136): 3.83e-60: 183: 95.59		HIRA_ARATH (1-1014): 5.21e-141: 450: 25.66
+	Dm
		53056 H3_DROME (1-136): 5.32e-59: 180: 97.06		A1Z898_DROME (1-699): 2.39e-91: 309: 19.87
+	Sc
		690852 H3_YEAST (1-136): 3.62e-54: 168: 90.44		HIR1_YEAST (1-854): 2.14e-91: 312: 17.78
+	Hs
		935208 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		TBL1R_HUMAN (9-257): 5.08e-48: 181: 18.82
+	Hs
		934716 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		CAF1B_HUMAN (221-727): 1.51e-28: 123: 12.63
+	Hs
		952307 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		CAF1B_HUMAN (221-727): 1.51e-28: 123: 12.63
+	Hs
		1024551 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		CAF1B_HUMAN (221-727): 1.51e-28: 123: 12.63
+	Hs
		1024562 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		CAF1B_HUMAN (221-727): 1.51e-28: 123: 12.63
+	Hs
		245614 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		TBL1X_HUMAN (168-360): 5.82e-23: 106: 18.67
+	Hs
		152879 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		APAF_HUMAN (5-185): 4.57e-21: 101: 17.06
+	Hs
		903117 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		WDR5_HUMAN (737-898): 2.19e-14: 77.5: 10.78
+	Hs
		903128 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		WDR5_HUMAN (737-898): 2.19e-14: 77.5: 10.78
+	Hs
		903260 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		WDR5_HUMAN (737-898): 2.19e-14: 77.5: 10.78
+	Hs
		792992 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		LIS1_HUMAN (630-897): 2.98e-13: 74.8: 7.64
+	Hs
		934971 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		DAW1_HUMAN (659-878): 4.47e-11: 68.3: 9.87
+	Hs
		934703 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		CDC20_HUMAN (66-205): 2.87e-10: 65.9: 31.03
+	Hs
		267767 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		TAF5L_HUMAN (103-246): 2.9e-09: 62.8: 30.67