HitPredict

Interactor 1: RPN1 (P87048)
26S proteasome regulatory subunit rpn1 (19S regulatory cap region of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Gene: RPN1

Interactor 2: DSK2 (Q10169)
Deubiquitination-protection protein dph1
Gene: dph1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11584278
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 891 Sp			1 354
+	Hs
		872151 PSMD2_HUMAN (1-885): 0: 1224: 47.36		RD23A_HUMAN (3-352): 8.51e-57: 190: 14.68
+	Sp
		251964 RPN1_SCHPO (1-891): 0: 1228: 100.00		RHP23_SCHPO (4-353): 2.14e-53: 181: 16.21
+	Rn
		1116239 PSMD2_RAT (1-885): 0: 1237: 48.02		RD23B_RAT (4-351): 3.12e-47: 166: 15.33
+	Hs
		872262 PSMD2_HUMAN (1-885): 0: 1224: 47.36		RD23B_HUMAN (4-351): 1.14e-47: 167: 16.54
+	Hs
		1027733 PSMD2_HUMAN (1-885): 0: 1224: 47.36		DDI1_HUMAN (4-268): 1.7e-47: 166: 14.80
+	Hs
		1027692 PSMD2_HUMAN (1-885): 0: 1224: 47.36		DDI2_HUMAN (4-268): 6.01e-43: 155: 15.52
+	Hs
		1027815 PSMD2_HUMAN (1-885): 0: 1224: 47.36		UBQL2_HUMAN (4-296): 9.42e-34: 133: 17.55
+	Hs
		1027821 PSMD2_HUMAN (1-885): 0: 1224: 47.36		UBQL1_HUMAN (4-295): 2.6e-33: 131: 19.46
+	Hs
		1027806 PSMD2_HUMAN (1-885): 0: 1224: 47.36		UBQL4_HUMAN (4-317): 1.38e-28: 118: 16.95
+	Hs
		923974 PSMD2_HUMAN (1-885): 0: 1224: 47.36		RS27A_HUMAN (4-91): 1.4e-31: 118: 23.86
+	At
		1195577 PSD2A_ARATH (3-885): 0: 1148: 46.77		RD23C_ARATH (4-354): 6.86e-55: 187: 13.88
+	Dm
		1374998 Q9VW54_DROME (41-885): 0: 1064: 46.89		Q9VWD9_DROME (4-299): 7.91e-31: 124: 18.86
+	Sc
		753873 RPN1_YEAST (50-885): 0: 901: 39.42		DSK2_YEAST (3-352): 3.76e-55: 186: 38.65
+	Sc
		697080 RPN1_YEAST (50-885): 0: 901: 39.42		RAD23_YEAST (4-353): 1.24e-47: 167: 14.75
+	Hs
		872202 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		RD23A_HUMAN (3-352): 8.51e-57: 190: 14.68
+	Hs
		872303 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		RD23B_HUMAN (4-351): 1.14e-47: 167: 16.54
+	Hs
		1259550 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		DDI1_HUMAN (4-268): 1.7e-47: 166: 14.80
+	Hs
		1136649 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		DDI2_HUMAN (4-268): 6.01e-43: 155: 15.52
+	Hs
		1303937 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		UBQL4_HUMAN (4-317): 1.38e-28: 118: 16.95
+	Hs
		924124 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		RS27A_HUMAN (4-91): 1.4e-31: 118: 23.86