HitPredict

Interactor 1: RPN1 (P87048)
26S proteasome regulatory subunit rpn1 (19S regulatory cap region of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Gene: RPN1

Interactor 2: PSA4 (Q10329)
Probable proteasome subunit alpha type-4
Gene: pre6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	20133687, 28784663
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0034399 - nuclear periphery GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 891 Sp			1 259
+	Hs
		156281 PSMD2_HUMAN (1-885): 0: 1224: 47.36		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Sp
		953217 RPN1_SCHPO (1-891): 0: 1228: 100.00		PSA5_SCHPO (2-237): 5.79e-94: 278: 32.79
+	Hs
		637407 PSMD2_HUMAN (1-885): 0: 1224: 47.36		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		656214 PSMD2_HUMAN (1-885): 0: 1224: 47.36		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Sp
		953201 RPN1_SCHPO (1-891): 0: 1228: 100.00		PSA3_SCHPO (1-238): 2.11e-89: 266: 32.26
+	Hs
		893662 PSMD2_HUMAN (1-885): 0: 1224: 47.36		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Sp
		293713 RPN1_SCHPO (1-891): 0: 1228: 100.00		PSA2_SCHPO (4-211): 2.04e-44: 151: 37.44
+	Hs
		637679 PSMD2_HUMAN (1-885): 0: 1224: 47.36		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10
+	Dm
		1278652 Q9VW54_DROME (41-885): 0: 1064: 46.89		PSA5_DROME (2-233): 1.76e-93: 277: 34.44
+	Dm
		611672 Q9VW54_DROME (41-885): 0: 1064: 46.89		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Dm
		771325 Q9VW54_DROME (41-885): 0: 1064: 46.89		PSA2_DROME (4-212): 3.06e-48: 161: 37.92
+	Sc
		753833 RPN1_YEAST (50-885): 0: 901: 39.42		PSA4_YEAST (1-232): 5.22e-93: 275: 58.48
+	Sc
		689178 RPN1_YEAST (50-885): 0: 901: 39.42		PSA5_YEAST (2-245): 1.62e-91: 272: 32.54
+	Hs
		156342 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		637529 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		656297 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Hs
		893734 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Sc
		693311 RPN2_YEAST (60-822): 4.16e-145: 455: 18.37		PSA4_YEAST (1-232): 5.22e-93: 275: 58.48
+	Sc
		689159 RPN2_YEAST (60-822): 4.16e-145: 455: 18.37		PSA5_YEAST (2-245): 1.62e-91: 272: 32.54
+	Hs
		637734 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10