HitPredict

Interactor 1: RPN1 (P87048)
26S proteasome regulatory subunit rpn1 (19S regulatory cap region of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Gene: RPN1

Interactor 2: UBP6 (Q92353)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thiollesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: UBP6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	15533439, 20838651
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 891 Sp			1 468
+	Hs
		870787 PSMD2_HUMAN (1-885): 0: 1224: 47.36		UBP14_HUMAN (2-467): 6.19e-99: 307: 36.31
+	Hs
		1027744 PSMD2_HUMAN (1-885): 0: 1224: 47.36		UBP7_HUMAN (92-403): 4.49e-65: 228: 18.98
+	Hs
		1027735 PSMD2_HUMAN (1-885): 0: 1224: 47.36		UBCP1_HUMAN (1-76): 1.34e-09: 61.2: 41.25
+	Zm
		17878 A0A1D6H0T6_MAIZE (46-885): 0: 1119: 48.54		A0A1D6JSI9_MAIZE (88-319): 1.48e-27: 118: 21.60
+	Sc
		753859 RPN1_YEAST (50-885): 0: 901: 39.42		UBP6_YEAST (6-463): 5.16e-95: 297: 36.59
+	Sc
		753883 RPN1_YEAST (50-885): 0: 901: 39.42		UBP15_YEAST (51-466): 1.24e-67: 236: 16.89
+	Sp
		251851 RPN2_SCHPO (350-820): 9.6e-136: 431: 22.31		UBP6_SCHPO (1-468): 3.64e-141: 414: 100.00
+	Hs
		870881 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		UBP14_HUMAN (2-467): 6.19e-99: 307: 36.31
+	Sc
		693324 RPN2_YEAST (60-822): 4.16e-145: 455: 18.37		UBP6_YEAST (6-463): 5.16e-95: 297: 36.59
+	Hs
		1261995 PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43		UBCP1_HUMAN (1-76): 1.34e-09: 61.2: 41.25