HitPredict

Interactor 1: VP35B (F4I0P8)
Vacuolar protein sorting-associated protein 35B (Vesicle protein sorting 35B)
Gene: VPS35B

Interactor 2: VP26B (Q9T091)
Vacuolar protein sorting-associated protein 26B (Vesicle protein sorting 26B)
Gene: VPS26B

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	25681156
Identification Methods	two hybrid, protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Vps26~Vps35
Common GO terms	GO:0005794 - Golgi apparatus GO:0006886 - intracellular protein transport GO:0010008 - endosome membrane GO:0042147 - retrograde transport, endosome to Golgi
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 790 At			1 303
+	At
		95403 VP35B_ARATH (1-790): 0: 1189: 100.00		VP26A_ARATH (1-302): 1.19e-157: 443: 91.06
+	At
		1186819 VP35A_ARATH (6-790): 0: 1110: 68.53		VP26A_ARATH (1-302): 1.19e-157: 443: 91.06
+	Mm
		771794 VPS35_MOUSE (5-790): 0: 1038: 42.43		VP26A_MOUSE (1-300): 6.08e-154: 435: 57.81
+	Hs
		264737 VPS35_HUMAN (5-790): 0: 1036: 42.55		VP26A_HUMAN (1-300): 8.54e-154: 434: 58.14
+	Rn
		102535 G3V8A5_RAT (5-790): 0: 1035: 42.43		VP26A_RAT (1-300): 1.31e-153: 434: 57.81
+	Mm
		1207561 VPS35_MOUSE (5-790): 0: 1038: 42.43		VP26B_MOUSE (6-299): 2.84e-152: 431: 55.59
+	Hs
		1116285 VPS35_HUMAN (5-790): 0: 1036: 42.55		VP26B_HUMAN (6-299): 1.14e-152: 432: 55.59
+	Dm
		1376404 Q9W277_DROME (1-780): 0: 1024: 39.93		VPS26_DROME (1-301): 5.53e-153: 438: 54.31
+	Hs
		68621 VPS35_HUMAN (5-790): 0: 1036: 42.55		A8MY26_HUMAN (154-279): 4.51e-49: 162: 17.46
+	Sc
		710063 VPS35_YEAST (15-758): 0: 788: 30.56		PEP8_YEAST (4-298): 1.89e-114: 336: 31.15