HitPredict

Interactor 1: CAC1A (P91645)
Voltage-dependent calcium channel type A subunit alpha-1 (Protein cacophony) (Protein nightblind A) (Protein no-on-transient B) (Dmca1A)
Gene: cac

Interactor 2: Q86BS0 (Q86BS0)
RIM-binding protein, isoform O
Gene: Rbp

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	22174254, 32369542, 26274777
Identification Methods	two hybrid, pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031594 - neuromuscular junction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1851 Dm			1 1473
+	Rn
		869906 CAC1A_RAT (1085-1444): 6.41e-30: 132: 16.83		RIMB2_RAT (539-1445): 1.64e-111: 380: 29.45
+	Hs
		132270 CAC1A_HUMAN (1344-1782): 1.51e-09: 65.7: 10.11		RIMB2_HUMAN (515-1439): 6.17e-109: 373: 29.15
+	Hs
		1047193 CAC1C_HUMAN (1-347): 1.93e-42: 173: 15.37		NEO1_HUMAN (599-1358): 2.29e-38: 159: 10.29
+	Hs
		1018291 CAC1C_HUMAN (1-347): 1.93e-42: 173: 15.37		CNTN1_HUMAN (431-1054): 2.44e-36: 152: 10.57
+	Hs
		1031981 CAC1C_HUMAN (1-347): 1.93e-42: 173: 15.37		PTPRS_HUMAN (457-1203): 1.35e-27: 124: 10.77
+	Hs
		616972 CAC1C_HUMAN (1-347): 1.93e-42: 173: 15.37		PTPRD_HUMAN (488-1008): 3e-25: 116: 9.95
+	Hs
		1018310 SCN3A_HUMAN (1079-1272): 1.44e-21: 104: 21.72		CNTN1_HUMAN (431-1054): 2.44e-36: 152: 10.57
+	Hs
		489959 CAC1C_HUMAN (1-347): 1.93e-42: 173: 15.37		PTPRF_HUMAN (660-871): 9.78e-15: 82: 16.59
+	Hs
		1047269 CAC1C_HUMAN (1-347): 1.93e-42: 173: 15.37		ROBO2_HUMAN (455-1006): 2.94e-14: 80.5: 11.84
+	Hs
		1047182 CAC1C_HUMAN (1-347): 1.93e-42: 173: 15.37		TITIN_HUMAN (544-1003): 1.17e-11: 72.3: 10.52
+	Hs
		1032019 SCN2A_HUMAN (1079-1365): 1.55e-22: 108: 17.75		PTPRS_HUMAN (457-1203): 1.35e-27: 124: 10.77
+	Hs
		132278 CAC1A_HUMAN (1344-1782): 1.51e-09: 65.7: 10.11		RIMB1_HUMAN (682-1464): 5.62e-14: 79.7: 13.76