HitPredict

Interactor 1: MAX (P91664)
Protein max (dMax) (Myc-associated factor X)
Gene: MAX

Interactor 2: MYC (Q9W4S7)
Myc protein (Diminutive protein) (dMyc1)
Gene: MYC

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.918

Property	Details
Experiments	27626673, 19165923, 14605208, 17898168, unassigned4
Identification Methods	affinity chromatography technology, two hybrid, pull down, experimental interaction detection
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 161 Dm			1 717
+	Hs
		347688 MNT_HUMAN (24-154): 6.89e-27: 107: 22.90		MYC_HUMAN (455-714): 1.7e-58: 206: 28.14
+	At
		222008 MYC4_ARATH (2-159): 1.08e-30: 117: 21.34		MYC2_ARATH (446-710): 2.53e-40: 158: 18.68
+	At
		1107218 MYC2_ARATH (1-155): 8.57e-27: 106: 21.21		MYC2_ARATH (446-710): 2.53e-40: 158: 18.68
+	Hs
		607791 SRBP1_HUMAN (8-152): 5.99e-31: 119: 18.00		USF1_HUMAN (438-713): 8.43e-34: 133: 15.41
+	Hs
		1304735 MNT_HUMAN (24-154): 6.89e-27: 107: 22.90		MNT_HUMAN (497-711): 1.18e-35: 144: 20.54
+	Hs
		607822 USF2_HUMAN (20-131): 1.69e-29: 111: 25.21		USF1_HUMAN (438-713): 8.43e-34: 133: 15.41
+	Hs
		1304736 MNT_HUMAN (24-154): 6.89e-27: 107: 22.90		MAD3_HUMAN (583-706): 3.14e-32: 125: 23.81
+	Hs
		1079719 USF2_HUMAN (20-131): 1.69e-29: 111: 25.21		USF2_HUMAN (488-711): 5.62e-28: 117: 18.57
+	At
		222004 MYC4_ARATH (2-159): 1.08e-30: 117: 21.34		MYC4_ARATH (491-716): 3.96e-23: 106: 16.59
+	At
		222019 MYC4_ARATH (2-159): 1.08e-30: 117: 21.34		MYC3_ARATH (503-701): 2.19e-22: 103: 16.58
+	Mm
		1376696 SRBP1_MOUSE (8-156): 4.1e-30: 116: 18.18		SRBP1_MOUSE (449-705): 1.85e-21: 102: 13.95
+	Hs
		738941 SRBP1_HUMAN (8-152): 5.99e-31: 119: 18.00		SRBP1_HUMAN (421-705): 3.88e-20: 98: 13.68
+	Mm
		139904 MNT_MOUSE (24-158): 3.08e-28: 111: 22.22		MAX_MOUSE (602-714): 2.38e-23: 98.8: 25.00
+	At
		1107239 MYC2_ARATH (1-155): 8.57e-27: 106: 21.21		MYC3_ARATH (503-701): 2.19e-22: 103: 16.58
+	Gg
		348453 MYC_CHICK (23-123): 1.57e-26: 105: 30.39		MAX_CHICK (602-716): 7.26e-24: 100: 24.59
+	Hs
		898182 MNT_HUMAN (24-154): 6.89e-27: 107: 22.90		MAX_HUMAN (602-714): 6.64e-23: 97.6: 25.00
+	Rn
		449464 MYC_RAT (23-123): 1.7e-26: 105: 28.43		MAX_RAT (602-714): 2.14e-23: 99.2: 25.00
+	Hs
		738962 SRBP2_HUMAN (34-153): 3.61e-26: 105: 19.20		SRBP1_HUMAN (421-705): 3.88e-20: 98: 13.68
+	Hs
		983441 MNT_HUMAN (24-154): 6.89e-27: 107: 22.90		MAD1_HUMAN (583-708): 2.35e-16: 80.7: 19.84