Interactor 1: SMO (P91682)
Protein smoothened (dSMO) (SMOH) (Smooth)
Gene: SMO

Interactor 2: SMO (P91682)
Protein smoothened (dSMO) (SMOH) (Smooth)
Gene: SMO

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 17284519, 17960137, 20844016, 22537496, 26863604, 25009998
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Frizzled~Frizzled, Frizzled~Fz, Fz~Fz
Common GO terms GO:0001745 - compound eye morphogenesis
GO:0001746 - Bolwig's organ morphogenesis
GO:0002385 - mucosal immune response
GO:0004930 - G protein-coupled receptor activity
GO:0005113 - patched binding
and 26 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1036
Dm

1 1036
+ Hs
+ Rn
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs

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Last updated: 15 Jul 2024