HitPredict

Interactor 1: P91857 (P91857)
small monomeric GTPase (EC 3.6.5.2)
Gene: rab-5

Interactor 2: REP1 (Q9BKQ5)
Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (TCD protein)
Gene: rep-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19090809
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Ce			1 510
+	Hs
		678339 RAB5B_HUMAN (1-207): 2.59e-99: 288: 75.35		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Hs
		838618 RAB5B_HUMAN (1-207): 2.59e-99: 288: 75.35		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Mm
		838709 RAB1A_MOUSE (9-207): 1.71e-87: 258: 41.95		GDIA_MOUSE (5-496): 0: 581: 22.31
+	Dm
		1358727 RAB5_DROME (2-208): 4.73e-95: 277: 71.09		Q9VLB7_DROME (5-501): 0: 559: 22.84
+	Hs
		678344 RAB1A_HUMAN (9-207): 1.71e-87: 258: 41.95		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Hs
		838625 RAB1A_HUMAN (9-207): 1.71e-87: 258: 41.95		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Hs
		678394 RAB1B_HUMAN (12-207): 1.16e-85: 253: 41.29		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Hs
		838683 RAB1B_HUMAN (12-207): 1.16e-85: 253: 41.29		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Hs
		678343 RB11A_HUMAN (9-208): 2.68e-82: 245: 37.38		GDIA_HUMAN (5-496): 0: 578: 22.31
+	Hs
		838624 RB11A_HUMAN (9-208): 2.68e-82: 245: 37.38		GDIB_HUMAN (5-496): 0: 574: 21.91
+	Dm
		185501 O18332_DROME (9-207): 2.62e-85: 252: 40.49		Q9VLB7_DROME (5-501): 0: 559: 22.84
+	Hs
		622572 RAB5B_HUMAN (1-207): 2.59e-99: 288: 75.35		RAE1_HUMAN (1-73): 1.55e-24: 109: 43.84
+	Hs
		642723 RAB1A_HUMAN (9-207): 1.71e-87: 258: 41.95		RAE2_HUMAN (1-99): 2.18e-25: 112: 39.39
+	Hs
		622577 RAB1A_HUMAN (9-207): 1.71e-87: 258: 41.95		RAE1_HUMAN (1-73): 1.55e-24: 109: 43.84
+	Hs
		642743 RAB1B_HUMAN (12-207): 1.16e-85: 253: 41.29		RAE2_HUMAN (1-99): 2.18e-25: 112: 39.39
+	Hs
		622619 RAB1B_HUMAN (12-207): 1.16e-85: 253: 41.29		RAE1_HUMAN (1-73): 1.55e-24: 109: 43.84
+	Hs
		642722 RB11A_HUMAN (9-208): 2.68e-82: 245: 37.38		RAE2_HUMAN (1-99): 2.18e-25: 112: 39.39
+	Hs
		642730 RB11B_HUMAN (9-208): 8.25e-82: 244: 38.43		RAE2_HUMAN (1-99): 2.18e-25: 112: 39.39
+	Hs
		622576 RB11A_HUMAN (9-208): 2.68e-82: 245: 37.38		RAE1_HUMAN (1-73): 1.55e-24: 109: 43.84
+	Hs
		622590 RB11B_HUMAN (9-208): 8.25e-82: 244: 38.43		RAE1_HUMAN (1-73): 1.55e-24: 109: 43.84