HitPredict

Interactor 1: MCM6 (P97311)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Mis5 homolog)
Gene: MCM6

Interactor 2: ATRX (Q61687)
Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (HP1 alpha-interacting protein) (HP1-BP38 protein) (Heterochromatin protein 2) (X-linked nuclear protein)
Gene: ATRX

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34162889
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 821 Mm			1 2476
+	Hs
		802437 MCM6_HUMAN (1-821): 0: 900: 95.86		ATRX_HUMAN (1-2476): 0: 1016: 80.87
+	Mm
		956191 MCM2_MOUSE (10-732): 0: 661: 28.08		ATRX_MOUSE (1-2476): 0: 1129: 100.00
+	Hs
		802405 MCM2_HUMAN (10-732): 0: 661: 28.08		ATRX_HUMAN (1-2476): 0: 1016: 80.87
+	Hs
		708393 MCM4_HUMAN (2-738): 0: 659: 26.83		ATRX_HUMAN (1-2476): 0: 1016: 80.87
+	Hs
		708832 MCM7_HUMAN (22-732): 0: 622: 28.18		ATRX_HUMAN (1-2476): 0: 1016: 80.87
+	Mm
		1143053 MCM7_MOUSE (123-655): 5.73e-86: 290: 35.25		ATRX_MOUSE (1-2476): 0: 1129: 100.00
+	Hs
		1055555 MCM6_HUMAN (1-821): 0: 900: 95.86		CHD4_HUMAN (166-378): 7.45e-13: 76.9: 14.29
+	Sc
		667853 MCM5_YEAST (3-663): 0: 664: 28.77		ISW1_YEAST (1992-2212): 3.86e-57: 220: 28.07
+	Hs
		708618 MCM5_HUMAN (2-749): 0: 681: 27.26		CHD3_HUMAN (166-377): 2.11e-11: 72.3: 13.87
+	Hs
		627266 MCM3_HUMAN (13-813): 0: 664: 25.87		CHD4_HUMAN (166-378): 7.45e-13: 76.9: 14.29
+	Hs
		627247 MCM3_HUMAN (13-813): 0: 664: 25.87		CHD3_HUMAN (166-377): 2.11e-11: 72.3: 13.87
+	Hs
		832409 MCM2_HUMAN (10-732): 0: 661: 28.08		CHD3_HUMAN (166-377): 2.11e-11: 72.3: 13.87
+	Hs
		708880 MCM7_HUMAN (22-732): 0: 622: 28.18		CHD3_HUMAN (166-377): 2.11e-11: 72.3: 13.87