HitPredict

Interactor 1: DAB1 (P97318)
Disabled homolog 1
Gene: DAB1

Interactor 2: VLDLR (P98156)
Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)
Gene: VLDLR

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	10380922, 15249135, 10827173
Identification Methods	pull down, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0021517 - ventral spinal cord development GO:0045177 - apical part of cell GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Mm			1 873
+	Hs
		269133 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		VLDLR_HUMAN (19-873): 0: 713: 96.02
+	Mm
		956234 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		LRP8_MOUSE (9-325): 2.02e-31: 134: 31.52
+	Mm
		729617 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		LDLR_MOUSE (4-233): 5.33e-22: 104: 22.76
+	Mm
		69879 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		B1AXJ3_MOUSE (3-192): 8.66e-21: 100: 22.17
+	Hs
		269145 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LRP8_HUMAN (2-192): 4.41e-22: 104: 25.73
+	Hs
		269114 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LDLR_HUMAN (232-464): 3.03e-18: 92.2: 24.49
+	Hs
		269134 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LRP2_HUMAN (235-462): 1.29e-16: 87.6: 23.81
+	Mm
		57553 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		LRP2_MOUSE (270-464): 5.07e-10: 66: 20.10
+	Mm
		956233 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		LRP1_MOUSE (234-442): 3.01e-09: 63.3: 19.56
+	Hs
		269141 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LRP1_HUMAN (234-442): 8.45e-09: 61.7: 19.56
+	Hs
		351073 ARH_HUMAN (11-271): 2.37e-48: 172: 18.35		LDLR_HUMAN (232-464): 3.03e-18: 92.2: 24.49
+	Hs
		992719 GULP1_HUMAN (17-327): 2.41e-59: 201: 19.69		LRP1_HUMAN (234-442): 8.45e-09: 61.7: 19.56
+	Hs
		957612 ARH_HUMAN (11-271): 2.37e-48: 172: 18.35		LRP2_HUMAN (235-462): 1.29e-16: 87.6: 23.81
+	Hs
		957621 ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81		LRP2_HUMAN (235-462): 1.29e-16: 87.6: 23.81
+	Hs
		351065 DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47		LDLR_HUMAN (232-464): 3.03e-18: 92.2: 24.49
+	Hs
		992682 ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81		LRP1_HUMAN (234-442): 8.45e-09: 61.7: 19.56
+	Rn
		292326 DAB2_RAT (8-587): 1.04e-40: 159: 25.34		LRP2_RAT (219-460): 2.77e-12: 73.3: 18.36
+	Mm
		57558 ARH_MOUSE (8-271): 6.79e-45: 163: 16.67		LRP2_MOUSE (270-464): 5.07e-10: 66: 20.10
+	Mm
		57554 DAB2_MOUSE (8-587): 2.89e-40: 158: 25.71		LRP2_MOUSE (270-464): 5.07e-10: 66: 20.10
+	Hs
		270287 DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47		LRP6_HUMAN (4-73): 5.17e-09: 62.5: 29.17