HitPredict

Interactor 1: DAB1 (P97318)
Disabled homolog 1
Gene: DAB1

Interactor 2: LRP8 (Q924X6)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	10827173
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0021517 - ventral spinal cord development GO:0021766 - hippocampus development GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Mm			1 996
+	Hs
		269114 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LDLR_HUMAN (4-329): 9.79e-37: 151: 28.06
+	Mm
		956222 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		VLDLR_MOUSE (6-235): 1e-27: 123: 24.79
+	Hs
		269133 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		VLDLR_HUMAN (6-235): 2.77e-27: 121: 23.93
+	Hs
		269145 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LRP8_HUMAN (4-266): 2.83e-24: 111: 28.26
+	Mm
		729617 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		LDLR_MOUSE (5-187): 4.01e-14: 79.1: 21.72
+	Mm
		69879 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		B1AXJ3_MOUSE (4-161): 1.48e-12: 73.7: 16.67
+	Mm
		57553 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		LRP2_MOUSE (716-932): 1.76e-09: 64.5: 13.55
+	Mm
		956233 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		LRP1_MOUSE (78-241): 6.84e-09: 62.6: 26.90
+	Hs
		269141 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LRP1_HUMAN (62-337): 2.4e-09: 63.7: 14.19
+	Hs
		351073 ARH_HUMAN (11-271): 2.37e-48: 172: 18.35		LDLR_HUMAN (4-329): 9.79e-37: 151: 28.06
+	Hs
		269134 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		LRP2_HUMAN (725-932): 4.49e-09: 62.9: 11.81
+	Hs
		351065 DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47		LDLR_HUMAN (4-329): 9.79e-37: 151: 28.06
+	Hs
		992719 GULP1_HUMAN (17-327): 2.41e-59: 201: 19.69		LRP1_HUMAN (62-337): 2.4e-09: 63.7: 14.19
+	Hs
		270287 DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47		LRP6_HUMAN (245-429): 2.07e-14: 80.3: 21.58
+	Hs
		957612 ARH_HUMAN (11-271): 2.37e-48: 172: 18.35		LRP2_HUMAN (725-932): 4.49e-09: 62.9: 11.81
+	Hs
		992682 ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81		LRP1_HUMAN (62-337): 2.4e-09: 63.7: 14.19
+	Hs
		957621 ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81		LRP2_HUMAN (725-932): 4.49e-09: 62.9: 11.81
+	Mm
		57558 ARH_MOUSE (8-271): 6.79e-45: 163: 16.67		LRP2_MOUSE (716-932): 1.76e-09: 64.5: 13.55
+	Rn
		292326 DAB2_RAT (8-587): 1.04e-40: 159: 25.34		LRP2_RAT (724-932): 3.05e-09: 63.7: 12.19
+	Mm
		57554 DAB2_MOUSE (8-587): 2.89e-40: 158: 25.71		LRP2_MOUSE (716-932): 1.76e-09: 64.5: 13.55