HitPredict

Interactor 1: SMRC1 (P97496)
SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1) (SWI3-related protein) (BAF155)
Gene: Smarcc1

Interactor 2: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0045597 - positive regulation of cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1104 Mm			1 319
+	Hs
		818323 SMRC1_HUMAN (29-1074): 0: 1088: 96.37		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Mm
		818694 SMRC1_MOUSE (29-1074): 0: 1079: 100.00		SOX2_MOUSE (1-319): 1.13e-62: 203: 98.43
+	Hs
		1272921 SMRC1_HUMAN (29-1074): 0: 1088: 96.37		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		818829 SMRC1_HUMAN (29-1074): 0: 1088: 96.37		SOX9_HUMAN (27-262): 3.13e-35: 135: 27.24
+	Hs
		1199176 SMRC1_HUMAN (29-1074): 0: 1088: 96.37		PB1_HUMAN (8-232): 6.76e-34: 133: 14.67
+	Hs
		996811 SMRC1_HUMAN (29-1074): 0: 1088: 96.37		SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71
+	Hs
		1272928 SMRC1_HUMAN (29-1074): 0: 1088: 96.37		SOX7_HUMAN (2-301): 1.16e-26: 110: 25.71
+	Hs
		818277 SMRC2_HUMAN (31-1104): 0: 905: 58.13		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Mm
		1142003 SMRC2_MOUSE (31-1104): 0: 885: 58.18		Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00
+	Hs
		818822 SMRC2_HUMAN (31-1104): 0: 905: 58.13		SOX9_HUMAN (27-262): 3.13e-35: 135: 27.24
+	Hs
		1199164 SMRC2_HUMAN (31-1104): 0: 905: 58.13		PB1_HUMAN (8-232): 6.76e-34: 133: 14.67
+	Hs
		1251615 SMRC2_HUMAN (31-1104): 0: 905: 58.13		SOX7_HUMAN (2-301): 1.16e-26: 110: 25.71
+	Hs
		818668 NCOR2_HUMAN (613-1103): 1.62e-38: 159: 14.21		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		727832 NCOR2_HUMAN (613-1103): 1.62e-38: 159: 14.21		SOX5_HUMAN (17-129): 1.06e-39: 150: 40.71
+	Hs
		225812 NCOR2_HUMAN (613-1103): 1.62e-38: 159: 14.21		SOX15_HUMAN (13-179): 7.82e-39: 138: 47.93
+	Hs
		160162 HGS_HUMAN (715-1103): 1.79e-37: 153: 17.66		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		727951 NCOR2_HUMAN (613-1103): 1.62e-38: 159: 14.21		SOX6_HUMAN (18-202): 1.01e-33: 132: 29.73
+	Hs
		1332335 NCOR2_HUMAN (613-1103): 1.62e-38: 159: 14.21		SOX17_HUMAN (17-285): 5.22e-31: 122: 26.02
+	Hs
		1311943 NCOR2_HUMAN (613-1103): 1.62e-38: 159: 14.21		SOX7_HUMAN (2-301): 1.16e-26: 110: 25.71
+	Hs
		881837 NCOR2_HUMAN (613-1103): 1.62e-38: 159: 14.21		SOX10_HUMAN (27-318): 1.19e-26: 110: 24.35