Interactor 1: EYA1 (P97767)
Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48)
Gene: EYA1

Interactor 2: SIX2 (Q62232)
Homeobox protein SIX2 (Sine oculis homeobox homolog 2)
Gene: SIX2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 11950062, 16024294, 11734542, 20956555
Identification Methods two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hydrolase~SIX1_SD
Common GO terms GO:0001656 - metanephros development
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007501 - mesodermal cell fate specification
GO:0042474 - middle ear morphogenesis
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 591
Mm

1 296
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024