HitPredict

Interactor 1: CRY1 (P97784)
Cryptochrome-1
Gene: CRY1

Interactor 2: FXL21 (Q8BFZ4)
F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box and leucine-rich repeat protein 3B) (F-box/LRR-repeat protein 3B)
Gene: Fbxl21

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	23452855, 23452856
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043153 - entrainment of circadian clock by photoperiod
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 606 Mm			1 434
+	Mm
		956905 CRY1_MOUSE (1-606): 0: 895: 100.00		FBXL3_MOUSE (17-434): 0: 727: 74.64
+	Hs
		1082162 CRY1_HUMAN (1-606): 0: 806: 92.41		FXL21_HUMAN (1-434): 0: 761: 85.95
+	Hs
		1082163 CRY1_HUMAN (1-606): 0: 806: 92.41		FBXL3_HUMAN (30-434): 0: 733: 76.79
+	Mm
		1206353 CRY2_MOUSE (2-505): 0: 678: 80.36		FXL21_MOUSE (1-434): 0: 807: 100.00
+	Hs
		1115766 CRY2_HUMAN (3-505): 0: 674: 80.32		FXL21_HUMAN (1-434): 0: 761: 85.95
+	Hs
		1115767 CRY2_HUMAN (3-505): 0: 674: 80.32		FBXL3_HUMAN (30-434): 0: 733: 76.79
+	Mm
		1207952 CRY2_MOUSE (2-505): 0: 678: 80.36		FBXL3_MOUSE (17-434): 0: 727: 74.64