HitPredict

Interactor 1: CRY1 (P97784)
Cryptochrome-1
Gene: CRY1

Interactor 2: FBXL3 (Q8C4V4)
F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A) (Protein after-hours) (Protein overtime)
Gene: FBXL3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.695

Property	Details
Experiments	30655559, 17462724, 23452855, 23452856
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0042752 - regulation of circadian rhythm GO:0043153 - entrainment of circadian clock by photoperiod
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 606 Mm			1 428
+	Hs
		1082163 CRY1_HUMAN (1-606): 0: 806: 92.41		FBXL3_HUMAN (1-428): 0: 818: 97.20
+	Mm
		956903 CRY1_MOUSE (1-606): 0: 895: 100.00		FXL21_MOUSE (19-428): 0: 724: 75.18
+	Hs
		1082162 CRY1_HUMAN (1-606): 0: 806: 92.41		FXL21_HUMAN (16-428): 0: 718: 72.73
+	Mm
		1207952 CRY2_MOUSE (2-505): 0: 678: 80.36		FBXL3_MOUSE (1-428): 0: 821: 100.00
+	Hs
		1115767 CRY2_HUMAN (3-505): 0: 674: 80.32		FBXL3_HUMAN (1-428): 0: 818: 97.20
+	Mm
		1206353 CRY2_MOUSE (2-505): 0: 678: 80.36		FXL21_MOUSE (19-428): 0: 724: 75.18
+	Hs
		1115766 CRY2_HUMAN (3-505): 0: 674: 80.32		FXL21_HUMAN (16-428): 0: 718: 72.73