HitPredict

Interactor 1: DLGP1 (P97836)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (rGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: Dlgap1

Interactor 2: GRIP1 (P97879)
Glutamate receptor-interacting protein 1 (GRIP-1) (AMPA receptor-interacting protein GRIP1)
Gene: GRIP1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11178875
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GKAP~PDZ_6
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0045211 - postsynaptic membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 992 Rn			1 1112
+	Mm
		1257407 DLGP1_MOUSE (1-992): 0: 1374: 98.49		MPDZ_MOUSE (150-1112): 2e-39: 162: 12.96
+	Rn
		291496 DLGP1_RAT (1-992): 0: 1379: 100.00		MAGI2_RAT (247-1111): 3.79e-31: 134: 11.60
+	Rn
		956992 DLGP1_RAT (1-992): 0: 1379: 100.00		DLG2_RAT (932-1112): 1.39e-18: 93.6: 18.52
+	Rn
		956990 DLGP1_RAT (1-992): 0: 1379: 100.00		DLG3_RAT (790-1104): 3.84e-18: 92.4: 15.15
+	Hs
		145951 DLGP1_HUMAN (1-992): 0: 1355: 94.46		MAGI2_HUMAN (13-456): 2.19e-25: 116: 13.60
+	Mm
		1265187 DLGP1_MOUSE (1-992): 0: 1374: 98.49		DLG2_MOUSE (932-1112): 1.55e-18: 93.6: 18.52
+	Rn
		677775 DLGP1_RAT (1-992): 0: 1379: 100.00		DLG4_RAT (945-1087): 6.29e-17: 88.2: 18.67
+	Mm
		1143504 DLGP1_MOUSE (1-992): 0: 1374: 98.49		DLG4_MOUSE (945-1087): 6.79e-17: 88.2: 19.33
+	Rn
		956989 DLGP1_RAT (1-992): 0: 1379: 100.00		DLG1_RAT (940-1075): 3.8e-13: 76.3: 17.52
+	Mm
		1195008 DLGP1_MOUSE (1-992): 0: 1374: 98.49		DLG1_MOUSE (940-1075): 1.98e-13: 77: 17.52
+	Hs
		145949 DLGP1_HUMAN (1-992): 0: 1355: 94.46		DLG2_HUMAN (932-1112): 3.81e-18: 92.4: 18.52
+	Mm
		936189 DLGP1_MOUSE (1-992): 0: 1374: 98.49		DLG3_MOUSE (867-1086): 2.41e-12: 73.4: 13.66
+	Hs
		145945 DLGP1_HUMAN (1-992): 0: 1355: 94.46		DLG4_HUMAN (945-1087): 7.28e-17: 87.8: 18.67
+	Hs
		145947 DLGP1_HUMAN (1-992): 0: 1355: 94.46		DLG1_HUMAN (965-1075): 1.45e-13: 77.4: 19.64
+	Hs
		145952 DLGP1_HUMAN (1-992): 0: 1355: 94.46		DLG3_HUMAN (888-1086): 1.45e-12: 74.2: 15.64
+	Hs
		1077291 DLGP2_HUMAN (1-992): 0: 1115: 51.55		DLG2_HUMAN (932-1112): 3.81e-18: 92.4: 18.52
+	Hs
		942392 DLGP2_HUMAN (1-992): 0: 1115: 51.55		DLG4_HUMAN (945-1087): 7.28e-17: 87.8: 18.67
+	Hs
		1021580 DLGP2_HUMAN (1-992): 0: 1115: 51.55		DLG1_HUMAN (965-1075): 1.45e-13: 77.4: 19.64
+	Hs
		4617 A0A1B0GTN4_HUMAN (1-992): 0: 1115: 51.55		DLG1_HUMAN (965-1075): 1.45e-13: 77.4: 19.64
+	Hs
		4619 A0A1B0GTN4_HUMAN (1-992): 0: 1115: 51.55		DLG3_HUMAN (888-1086): 1.45e-12: 74.2: 15.64