HitPredict

Interactor 1: IDD (P98153)
Integral membrane protein DGCR2/IDD
Gene: DGCR2

Interactor 2: ADA33 (Q9BZ11)
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM 33) (EC 3.4.24.-)
Gene: ADAM33

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ADAM_CR~Lectin_C
Common GO terms	GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 813
+	Hs
		957505 IDD_HUMAN (1-550): 4.55e-155: 456: 100.00		ADA30_HUMAN (48-739): 2.61e-134: 420: 28.82
+	Hs
		258342 LRP5_HUMAN (96-376): 2.01e-19: 94.5: 11.66		ADA33_HUMAN (1-813): 0: 581: 100.00
+	Hs
		270325 LRP6_HUMAN (178-357): 9.85e-13: 73.4: 9.47		ADA33_HUMAN (1-813): 0: 581: 100.00
+	Hs
		1034746 ST14_HUMAN (105-327): 1.58e-09: 62.9: 12.45		ADAM9_HUMAN (1-786): 0: 559: 31.66
+	Hs
		258361 LRP5_HUMAN (96-376): 2.01e-19: 94.5: 11.66		ADA30_HUMAN (48-739): 2.61e-134: 420: 28.82
+	Hs
		270347 LRP6_HUMAN (178-357): 9.85e-13: 73.4: 9.47		ADA30_HUMAN (48-739): 2.61e-134: 420: 28.82
+	Hs
		351114 LDLR_HUMAN (219-365): 4.15e-10: 64.5: 11.18		ADA30_HUMAN (48-739): 2.61e-134: 420: 28.82
+	Hs
		1356433 ST14_HUMAN (105-327): 1.58e-09: 62.9: 12.45		ADA30_HUMAN (48-739): 2.61e-134: 420: 28.82
+	Hs
		257241 LRP5_HUMAN (96-376): 2.01e-19: 94.5: 11.66		ATS4_HUMAN (37-668): 6.58e-121: 386: 19.74
+	Hs
		257242 LRP6_HUMAN (178-357): 9.85e-13: 73.4: 9.47		ATS4_HUMAN (37-668): 6.58e-121: 386: 19.74
+	Hs
		254302 LRP4_HUMAN (1-165): 6.73e-15: 80.3: 14.71		ATS1_HUMAN (33-672): 3.79e-110: 361: 19.70
+	Hs
		1255819 ST14_HUMAN (105-327): 1.58e-09: 62.9: 12.45		ATS15_HUMAN (17-669): 4.02e-111: 363: 18.99
+	Hs
		1355482 ST14_HUMAN (105-327): 1.58e-09: 62.9: 12.45		ATS1_HUMAN (33-672): 3.79e-110: 361: 19.70
+	Hs
		270283 LRP6_HUMAN (178-357): 9.85e-13: 73.4: 9.47		ATS12_HUMAN (33-798): 5.21e-103: 350: 15.62
+	Hs
		152344 TEN3_HUMAN (15-419): 5.76e-65: 232: 10.69		ADA10_HUMAN (196-519): 4.29e-23: 107: 27.63
+	Hs
		152356 ST14_HUMAN (105-327): 1.58e-09: 62.9: 12.45		ADA10_HUMAN (196-519): 4.29e-23: 107: 27.63
+	Dm
		1368973 Q9W4Y4_DROME (94-326): 2.01e-10: 66: 7.90		Q9VJW9_DROME (298-519): 2e-17: 89.4: 29.30