HitPredict

Interactor 1: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Interactor 2: IFIX (Q6K0P9)
Pyrin and HIN domain-containing protein 1 (Interferon-inducible protein X)
Gene: PYHIN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	28077445, 25665578
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 4391 Hs			1 492
+	Hs
		129779 AGRIN_HUMAN (4151-4365): 7.12e-18: 94.4: 32.14		IFIX_HUMAN (1-492): 0: 670: 100.00
+	Hs
		1144533 EGFLA_HUMAN (4143-4391): 4.03e-14: 81.6: 29.92		IFIX_HUMAN (1-492): 0: 670: 100.00
+	Hs
		172677 LAMA5_HUMAN (725-800): 4.51e-10: 68.7: 29.11		IFIX_HUMAN (1-492): 0: 670: 100.00
+	Hs
		502841 LAMC1_HUMAN (1562-1709): 9.78e-10: 67.3: 22.73		IFIX_HUMAN (1-492): 0: 670: 100.00
+	Hs
		631072 LAMA1_HUMAN (3800-4223): 5.66e-09: 65: 12.14		IFIX_HUMAN (1-492): 0: 670: 100.00
+	Hs
		1085769 OBSCN_HUMAN (2318-2544): 7.66e-09: 64.7: 13.12		IF16_HUMAN (112-405): 1.19e-62: 219: 36.55