Interactor 1: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Interactor 2: FNDC5 (Q8NAU1)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
Gene: FNDC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~fn3, Ig_3~fn3, Laminin_EGF~fn3
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 4391
Hs

1 212
+ Mm
+ Mm
+ Mm
+ Mm

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Last updated: 15 Jul 2024