HitPredict

Interactor 1: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Interactor 2: APBA2 (Q99767)
Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2)
Gene: APBA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	10827173
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0015031 - protein transport
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 4655 Hs			1 749
+	Hs
		957608 LRP2_HUMAN (1-4655): 0: 3803: 100.00		DLG2_HUMAN (259-730): 6.71e-46: 178: 10.96
+	Hs
		942324 LRP2_HUMAN (1-4655): 0: 3803: 100.00		DLG4_HUMAN (559-730): 2.89e-34: 142: 17.50
+	Hs
		957631 LRP2_HUMAN (1-4655): 0: 3803: 100.00		DLG3_HUMAN (403-730): 4.42e-26: 116: 13.19
+	Mm
		57555 LRP2_MOUSE (22-4655): 0: 3723: 76.66		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Hs
		1048453 LRP8_HUMAN (3464-3669): 8.96e-14: 80.7: 21.92		APBA2_HUMAN (1-749): 0: 777: 100.00
+	Hs
		992700 LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59		APBA2_HUMAN (1-749): 0: 777: 100.00
+	Hs
		970699 LRP8_HUMAN (3464-3669): 8.96e-14: 80.7: 21.92		APBA1_HUMAN (57-749): 9.83e-164: 495: 54.09
+	Hs
		942339 LRP8_HUMAN (3464-3669): 8.96e-14: 80.7: 21.92		DLG4_HUMAN (559-730): 2.89e-34: 142: 17.50
+	Mm
		1143476 LRP8_MOUSE (2623-2869): 2.33e-11: 72.6: 16.36		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Mm
		69882 B1AXJ3_MOUSE (3424-3628): 4.43e-11: 71.8: 12.50		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Mm
		1143471 LRP1_MOUSE (3672-3974): 3.08e-09: 66: 10.16		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Hs
		942331 LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59		DLG4_HUMAN (559-730): 2.89e-34: 142: 17.50