HitPredict

Interactor 1: XIAP (P98170)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Interactor 2: HTRA1 (Q92743)
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)
Gene: HTRA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.629

The method score is based on:

Property Details
Experiments 21387310, 28642151
Identification Methods affinity chromatography technology, pull down, protease assay
Interaction Type physical association, direct interaction, protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 497
Hs

1 480
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024